Clinical studies
The positive effects of physical activity and exercise for cancer patients have been proven through numerous observational studies. What is still lacking, however, are large-scale clinical, randomised studies which support these findings. The main objective of such studies is to find out in what exact "dosage" physical activity can help a cancer patient. In a similar way to a medicine, this involves finding out the right amount, that is frequency, duration and intensity of each exercise session. The "dosage" in this context is also dependent on the type of cancer, and how potential mechanisms of specific cancers can be influenced by physical activity.
Within the scope of studies, patients get the chance to benefit from the latest research findings at an early stage. In the Munich area there are currently two exercise intervention studies at the Zentrum für Prävention und Sportmedizin (Centre for Prevention and Sports Medicine) at Klinikum rechts der Isar under the leadership of Herrn Univ. Prof. Dr. med. Martin Halle.
LIBRE: Lebensstilintervention bei gesunden und erkrankten BRCA1/2 Mutationsträgerinnen (Lifestyle intervention in the case of healthy and affected BRCA1/2 mutation carriers)
- Intervention over 3 years with sport-based activity and nutrition plan (monitored training and training at home
- Primary endpoint: feasibility and acceptance of lifestyle intervention, quality of life, fitness
- Secondary endpoints: coping with stress, optimism, BMI, fat intake, maximum fitness
F-PROTECT: feasibility study on the potential and role of tertiary prevention through exercise for patients with bowel cancer
- Intervention (monitored training and training at home) over a period of 12 months
- Recording of recruitment figures/quota, compliance with regards to training intervention, physical activity (MET-h/week) and physical fitness (VO2peak), drop-out rate, barriers to participation in training
In general, you should be well-informed prior to deciding to take part in a study - especially if the study involves the use of medication. The 'ONKO' internet portal of the Deutsche Krebsgesellschaft e. V. (German Cancer Society) has created a good overview on the topic under "Klinische Studien in der Krebstherapie – Informationen für Patienten" (clinical studies in cancer therapy - information for patients - full details only available in German).